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1

A Well-Defined Iron Catalyst for the Reduction of Bicarbonates and Carbon Dioxide to Formates, Alkyl Formates, and Formamides

Christopher Federsel, Albert Boddien, Dr. Ralf Jackstell, Reiko Jennerjahn, Prof. Dr. Paul J. Dyson, Dr. Rosario Scopelliti, Prof. Dr. Gabor Laurenczy, Prof. Dr. Matthias Beller

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 362 KB

english, 2010

2

Catalytic Hydrogenation of Carbon Dioxide and Bicarbonates with a Well-Defined Cobalt Dihydrogen Complex

Christopher Federsel, Carolin Ziebart, Dr. Ralf Jackstell, Dr. Wolfgang Baumann, Prof. Dr. Matthias Beller

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

3

A guide to drug discovery: Logistics of process R&D: transforming laboratory methods to manufacturing scale

Federsel, Hans-Jürgen

Journal:

Nature Reviews Drug Discovery

Year:

2003

Language:

english

File:

PDF, 623 KB

english, 2003

4

Asymmetry on large scale: the roadmap to stereoselective processes

Federsel, Hans-Jürgen

Journal:

Nature Reviews Drug Discovery

Year:

2005

Language:

english

File:

PDF, 527 KB

english, 2005

5

Chemical Process Research and Development in the 21st Century: Challenges, Strategies, and Solutions from a Pharmaceutical Industry Perspective

Federsel, Hans-Jürgen

Journal:

Accounts of Chemical Research

Year:

2009

Language:

english

File:

PDF, 1.49 MB

english, 2009

6

En route to full implementation: driving the green chemistry agenda in the pharmaceutical industry

Federsel, Hans-Jürgen

Journal:

Green Chemistry

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

7

Mechanism of the Asymmetric Sulfoxidation in the Esomeprazole Process: Effects of the Imidazole Backbone for the Enantioselection

Muthu Seenivasaperumal, Hans-Jürgen Federsel, Kálmán J. Szabó

Journal:

Advanced Synthesis & Catalysis

Year:

2009

Language:

english

File:

PDF, 904 KB

english, 2009

8

Kohlenstoffdioxid-neutrale Wasserstoffspeicherung basierend auf Bicarbonaten und Formiaten

Albert Boddien, Felix Gärtner, Christopher Federsel, Peter Sponholz, Dörthe Mellmann, Dr. Ralf Jackstell, Dr. Henrik Junge, Prof. Matthias Beller

Journal:

Angewandte Chemie

Year:

2011

Language:

german

File:

PDF, 362 KB

german, 2011

9

Facing chirality in the 21st century: Approaching the challenges in the pharmaceutical industry

Hans-Jürgen Federsel

Journal:

Year:

2003

Language:

english

File:

PDF, 363 KB

english, 2003

10

Rise of inhaled toluene, ethyl benzene, m-xylene, or mesitylene in rat blood after treatment with ethanol

K. G. Römer, R. J. Federsel, K. J. Freundt

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1986

Language:

english

File:

PDF, 182 KB

english, 1986

11

Asymmetric Catalysis on Industrial Scale (Challenges, Approaches and Solutions) || Chiral Lactones by Asymmetric Hydrogenation - A Step Forward in (+)-Biotin Production

Blaser, Hans-Ulrich, Federsel, Hans-Jürgen

Year:

2010

Language:

english

File:

PDF, 151 KB

english, 2010

12

Chlorodifluoromethyl phenyl sulfone: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations

Zheng, Ji, Li, Ya, Zhang, Laijun, Hu, Jinbo, Meuzelaar, Gerrit Joost, Federsel, Hans-Jürgen

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 258 KB

english, 2007

13

Asymmetric Catalysis on Industrial Scale (Challenges, Approaches and Solutions) || Eliminating Barriers in Large-Scale Asymmetric Synthesis

Blaser, Hans-Ulrich, Federsel, Hans-Jürgen

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

14

Bumblebees in the city: abundance, species richness and diversity in two urban habitats

Gunnarsson, Bengt, Federsel, Lisa Marie

Journal:

Journal of Insect Conservation

Year:

2014

Language:

english

File:

PDF, 289 KB

english, 2014

15

Chirotechnology. Industrial synthesis of optically active compounds. Von Roger A. Sheldon. Marcel Dekker, New York, 1993. 423 S., geb. 145.00 $. – ISBN 0-8247-9143-6

Hans-Jürgen Federsel

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 289 KB

german, 1994

16

Moderne Katalysatoren zur Hydrierung von Kohlendioxid

Christopher Federsel, Ralf Jackstell, Matthias Beller

Journal:

Angewandte Chemie

Year:

2010

Language:

german

File:

PDF, 308 KB

german, 2010

17

Ein wohldefinierter Eisenkatalysator für die Reduktion von Bicarbonaten und Kohlendioxid zu Formiaten, Alkylformiaten und Formamiden

Christopher Federsel, Albert Boddien, Dr. Ralf Jackstell, Reiko Jennerjahn, Prof. Dr. Paul J. Dyson, Dr. Rosario Scopelliti, Prof. Dr. Gabor Laurenczy, Prof. Dr. Matthias Beller

Journal:

Angewandte Chemie

Year:

2010

Language:

german

File:

PDF, 344 KB

german, 2010

18

The Art of Process Chemistry. Herausgegeben von Nobuyoshi Yasuda.

Hans-Jürgen Federsel

Journal:

Angewandte Chemie

Year:

2011

Language:

german

File:

PDF, 251 KB

german, 2011

19

Book Review: Chirotechnology. Industrial Synthesis of Optically Active Compounds. By R. A. Sheldon

Hans Jürgen Federsel

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 261 KB

english, 1994

20

State-of-the-Art Catalysts for Hydrogenation of Carbon Dioxide

Christopher Federsel, Ralf Jackstell, Matthias Beller

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 359 KB

english, 2010

21

CO2-“Neutral” Hydrogen Storage Based on Bicarbonates and Formates

Albert Boddien, Felix Gärtner, Christopher Federsel, Peter Sponholz, Dörthe Mellmann, Dr. Ralf Jackstell, Dr. Henrik Junge, Prof. Matthias Beller

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 350 KB

english, 2011

22

The Art of Process Chemistry. Edited by Nobuyoshi Yasuda.

Hans-Jürgen Federsel

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

23

ChemInform Abstract: Development of a Full-Scale Process for a Chiral Pyrrolidine

Journal:

Year:

1997

File:

PDF, 24 KB

1997

24

Facing Chirality in the 21st Century: Approaching the Challenges in the Pharmaceutical Industry

Hans-Juergen Federsel

Journal:

Year:

2004

File:

PDF, 48 KB

2004

25

Asymmetry on Large Scale: The Roadmap to Stereoselective Processes

Hans-Juergen Federsel

Journal:

Year:

2005

File:

PDF, 8 KB

2005

26

ChemInform Abstract: Chemical Process Research and Development in the 21st Century: Challenges, Strategies, and Solutions from a Pharmaceutical Industry Perspective

Hans-Juergen Federsel

Journal:

Year:

2009

File:

PDF, 15 KB

2009

27

ChemInform Abstract: State-of-the-Art Catalysts for Hydrogenation of Carbon Dioxide

Christopher Federsel, Ralf Jackstell, Matthias Beller

Journal:

Year:

2011

File:

PDF, 20 KB

2011

28

Chirale Arzneimittel. Scale-up, Kontrolle und deren Bedeutung für die pharmazeutische Forschung

Hans-Jürgen Federsel

Journal:

Chemie in unserer Zeit

Year:

1993

Language:

german

File:

PDF, 1.51 MB

german, 1993

29

Ruthenium-Catalyzed Hydrogenation of Bicarbonate in Water

Christopher Federsel, Dr. Ralf Jackstell, Albert Boddien, Dr. Gabor Laurenczy, Prof. Matthias Beller

Journal:

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

30

Process R&D under the magnifying glass: Organization, business model, challenges, and scientific context

Hans-Jürgen Federsel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.99 MB

english, 2010

31

Structure and conformation of α,α,α-trifluoroanisol, C6H5OCF3

Daniela Federsel, Angelika Herrmann, Dines Christen, Stefan Sander, Helge Willner, Heinz Oberhammer

Journal:

Journal of Molecular Structure

Year:

2001

Language:

english

File:

PDF, 162 KB

english, 2001

32

A novel base-induced ring expansion of quaternized heterocycles

Hans-Jürgen Federsel, Jan Bergman

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 223 KB

english, 1980

33

Frühtherapie intraoperativer infektionen aufgrund bakteriologischer ergebnisse

F. Baumann, M. Federsel

Journal:

Archives of Orthopaedic and Trauma Surgery

Year:

1978

File:

PDF, 468 KB

1978

34

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP

Maria S. Humble, Karim E. Cassimjee, Maria Håkansson, Yengo R. Kimbung, Björn Walse, Vahak Abedi, Hans-Jürgen Federsel, Per Berglund, Derek T. Logan

Journal:

Year:

2012

Language:

english

File:

PDF, 497 KB

english, 2012

35

Cold-atom scanning probe microscopy

Gierling, M., Schneeweiss, P., Visanescu, G., Federsel, P., Häffner, M., Kern, D. P., Judd, T. E., Günther, A., Fortágh, J.

Journal:

Nature Nanotechnology

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

36

Start small, think big — the art of process R&D

Federsel, Hans-Jürgen

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

37

Key Amino Acid Residues for Reversed or Improved Enantiospecificity of an ω-Transaminase

Dr. Maria Svedendahl Humble, Karim Engelmark Cassimjee, Dr. Vahak Abedi, Dr. Hans-Jürgen Federsel, Prof. Per Berglund

Journal:

Year:

2012

Language:

english

File:

PDF, 388 KB

english, 2012

38

Decrease of inhaled toluene, ethyl benzene, m-xylene, or mesitylene in rat blood after combined exposure to ethyl acetate

K. J. Freundt, K. G. Römer, R. J. Federsel

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1989

Language:

english

File:

PDF, 196 KB

english, 1989

39

Examples of a unified nuclear reaction theory

H. Federsel, E.-J. Kanellopoulos, W. Sünkel, K. Wildermuth

Journal:

Physics Letters B

Year:

1970

Language:

english

File:

PDF, 200 KB

english, 1970

40

In search of sustainability: process R&D in light of current pharmaceutical industry challenges

Hans-Jürgen Federsel

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 596 KB

english, 2006

41

Drug discoverers –you need us!

Hans-Jürgen Federsel

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 25 KB

english, 2001

42

Drug discoverers – you need us! – Reply

Hans-Jürgen Federsel

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 18 KB

english, 2001

43

Building bridges from process R&D: from a customer–supplier relationship to full partnership

Hans-Jürgen Federsel

Journal:

Pharmaceutical Science & Technology Today

Year:

2000

Language:

english

File:

PDF, 138 KB

english, 2000

44

Optimization and Scale-up of a Pd-Catalyzed Aromatic C−N Bond Formation: A Key Step in the Synthesis of a Novel 5-HT1B Receptor Antagonist

Federsel, Hans-Jürgen, Hedberg, Martin, Tian, Wei

Journal:

Organic Process Research & Development

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

45

Regioisomerism in the Synthesis of a Chiral Aminotetralin Drug Compound: Unraveling Mechanistic Details and Diastereomer-Specific In-Depth NMR Investigations

Schuisky, Peter, Federsel, Hans-Jürgen, Tian, Wei

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 698 KB

english, 2012

46

Rapid Rearrangement of Quaternized Oxazoles and Thiazoles through Base Treatment

Federsel, Hans-Jürgen, Bergman, Jan

Journal:

Year:

1980

Language:

english

File:

PDF, 96 KB

english, 1980

47

Well-Defined Iron Catalyst for Improved Hydrogenation of Carbon Dioxide and Bicarbonate

Ziebart, Carolin, Federsel, Christopher, Anbarasan, Pazhamalai, Jackstell, Ralf, Baumann, Wolfgang, Spannenberg, Anke, Beller, Matthias

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 685 KB

english, 2012

48

Asymmetric Catalysis on Industrial Scale (Challenges, Approaches and Solutions) || Enabling Asymmetric Hydrogenation for the Design of Efficient Synthesis of Drug Substances

Blaser, Hans-Ulrich, Federsel, Hans-Jürgen

Year:

2010

Language:

english

File:

PDF, 444 KB

english, 2010

49

Development of a Process for a Chiral Aminochroman Antidepressant: A Case Story †

Federsel, Hans-Jürgen

Journal:

Organic Process Research & Development

Year:

2000

Language:

english

File:

PDF, 214 KB

english, 2000

50

Synthesis of Stable Phosphomide Ligands and their Use in Ru-Catalyzed Hydrogenations of Bicarbonate and Related Substrates

Gowrisankar, Saravanan, Federsel, Christopher, Neumann, Helfried, Ziebart, Carolin, Jackstell, Ralf, Spannenberg, Anke, Beller, Matthias

Journal:

Year:

2013

Language:

english

File:

PDF, 667 KB

english, 2013